Well Brutte (..) Should this go into production, there are plenty of m0's going for ~$1
But it is you who have to decide if that is for low volume (rip off some Nokia surplus and you already have the TFT, battery, charger and the case) or the mass production (BGA, 8-layer board, 4 generations of prototypes, at least). If that is a $5 BOM product then indeed 1$ or 2$ makes a difference when the plans are for hundreds of thousands to be manufactured. If you want to make 100 then it does not make sense to save $100 and dick around with $1 M0.
What is your BOM expectation? I suppose this is the very first thing you start from when your plans are to sell the thingy! What about googling "teardown" of similar products? Dave does that regularly and BOM is not a rocket science, just visit DigiKey, make a BOM list.
IIRC there was a pebble watch ripped apart some time ago, similar spec than yours. TFT, small, portable, battery powered low power, nothing fancy really. No GPS though.
What is the quantity needed?
If you insist on keeping key factors secret then I am afraid the topic won't go anywhere.