I just wanted to weigh in on this. I work for a university in Canada and we took a chance on LPKF. I completely agree with everything I've read in these forums - great hardware, glitchy software and awful support. Our S104 hasn't worked properly since we got it and its been completely out of commission for 5 months.
When we got the machine the USB cables needed to be replaced. They insisted I buy gold plated ones.
After replacing the USB cables the machine would hang up on tool check and the software would crash. As per the support instructions I pulled out the tool check dowel and cleaned it. Afterword it was too loose so I had to find the flow valve buried in the back of the machine and adjust. Took most of the day to calibrate the pressure on this one.
Finally we were milling boards...but then we had camera connectivity issues when running the solder paste dispenser.
After about a month of use, the S104 would just stop picking up tools altogether. They asked to send it back for repair, because we through out the crate that came with it we had to buy another for 400.00. Originally they said we would have to pay for one-way shipping then agreed to pay both ways after we hounded them.
They claimed they had solved the issue and sent it back a month later. Guess what...we're still having the same issues. They're now trying to blame it on the PC we're using. I've tried multiple PCs (all of which exceed the minimum spec listed in their manual).
I now have industry partners, researchers, students and instructors calling my constantly wanting to use this machine. For 30k, I really expected more from LPKF.