Yes, if you're ordering a few thousand+ 1-2 layer boards that get die-cut. Otherwise youre looking at laser routing (extra machine/step so definitely a cost-adder) or adding relief/clearance cuts, which will add a bit of cost if the board house has to move down to a smaller diameter cutter (slower feed for the mill, more time on the machine) though it should be minor if its just a tool change and detailing a few slots.