I made some tests:
to read the plots you can see on the top the voltage measured by the keithley 2000 and on the bottom the difference in voltage between the 3456 and the 2000. the hp 3245a is used as voltage source, can only do up to 10v but it's quite stable. All the participants were warmed up for at least 1h
1st test - 8V (10V range) for 20min:
They start quite close but quickly the 3456 drops, the rate of change diminishes over time and they seem to stabilise after 15min (-50uV in the first 5 minutes and then -20uV in the following 10minutes)
2nd test 1V ( 1V range)
With a 1v input there is no drift, they stay within 5uV from each other (20min test)
3rd test 5 to 10v (1v step on the 10v range) 10min per voltage step
there is drift on all ranges, but it seems to jump up at every increment. even if the previous step had time to stabilise the following higher voltage takes a few minutes to drift down some more.
4th test -10v,
I cannot see any drift here
5th test 10v on the 10v range, the 2000 measures tp 303, input of the ad converter, this should be 10v on full scale for each range. This one is measured with auto zero off
voltage on tp 303 drifts down with time but it's quite stable compared to the reading on the 3456, this would mean that the drift originates in the input amplifier
the resistance measure seems to work fine, but I can only test with 0.1% 25ppm/C resistors, so cannot really say if it's ok