Hi, that's the internal debug port, I was meaning to buy the Keysight U1173B optical cable from TME but when I login as a private person it's no longer possible to buy it and I couldn't be bothered to do it from my company: their loss...
I have had this
Sparkfun TTL adapter since forever, it is very convenient: in this case I power it from the multimeters own VCC, this creates the proper level shift voltage (black and red cables in the picture).
Then TX/RX is the yellow cables, I was meaning to close the meter back up (hence used long cables) but in the end I used a bench supply directly on the multimeters battery contacts to power it during the update...
The update tool that is linked on page-1 seems to have no problems to work with the USB to serial adapter I used (FTDI chipset) I guess it works with any serial device in Windows...