The Prius hybrid has an annoying feature. When the 12V battery falls below (I think, 11.5V) the car is effectively dead, and will not start. The only options are a boost or a dealer service call, even though the main hybrid battery may have plenty of charge in it.
What should happen is this: Pressing the start button should activate a controller which reads the charge level of both batteries, and if necessary, it should activate the DC to DC converter, delivering normal voltage to the 12 V system, thus allowing the car to start.
It would have to read the charge level of the 220 V hybrid battery to guard against allowing its charge level to fall below its lower threshold, before activating the DC-DC converter. If the 12V battery is completely dead, the controller could draw its small power requirement from either an on-board battery, or through a switch-mode power supply, drawing power from the hybrid battery.
It seems to me that someone who could design such a controller would have a very lucrative financial opportunity. There are millions of Prius hybrids out there with this problem. Parasitic drain is unavoidable and unpredictable with these cars, and I for one would welcome such a solution.