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Pretty sure I have interviewed that guy, on several occasions, and I am am very much afraid I have hired him once 
I watch for a skills list 20 items long on the resume. Then I dig into one or two, and inevitably we get an answer something such as, "Yeah, we had LabVIEW, like, for like one semester, and that was, like, really long ago... like a couple years ago."
And so they list it, and so they get rejected. Kind of like parts with bogus datasheets.
There's a tension here.
I can learn to use/do almost anything you want, on a time scale that is trivial in the context of a permanent (or even 2 - 3 year) job. I don't have time to learn everything that you *might* want, in advance of getting the job.
But if HR don't see their correct buzzwords listed on your CV then you don't even get the chance for an interview.
Simple example: C, C++, Obj-C, Java, C#, Python, Perl, Ruby, JavaScript, PHP, Kotlin, Scala, Swift, Go, Rust are all so similar that if you can program in one of them (especially if that one is C++ lol) then you can pick up any of the others quickly if you need to. But is anyone expert in *all* of them? Hell, no.
The same with assembly languages. I cut my teeth on 6502, Z80, PDP11, VAX, then moved on to 6809, 68000, PowerPC, MIPS, ARM, ARM64, RISC-V. I've even done .. ugh .. x86 from time to time .. e.g. 18 months ago I crested a simple scheme for on-the-fly mapping RISC-V instructions to x86_84 that outperformed QEMU by a factor of two and often ran RISC-V code on an i7 only 30% slower than gcc optimised native x86 code.
You've got some wacky home-grown programming language or CPU? I'm pretty sure I can cope...
Fortunately, there is a way around lying to the HR drones to get an interview and then being quizzed on stuff you don't actually know: approach the people you'll be working with (especially future supervisor) directly, or at least do something cool that they'll notice, and have THEM come to you and say "Why don't you come to work for us?" and then they *tell* HR to hire you.
My (spare time) work on the above-mentioned RISC-V emulator is one of the things that got the attention of SiFive and led to them hiring me. My work on the Boehm–Demers–Weiser garbage collector led to both Samsung and before them Mozilla offering me earlier jobs. The vast majority of other jobs have come from getting someone to introduce me to their boss.
In 35 years I've only got *one* (1) job via the traditional job agency/CV route. Shotgun sending out of CVs is a mug's game, and heck of a depressing.