I see no real advantages. You still deal with their substrate that is then wire-bonded to the package with LGA pads (I guess other packages may be available too).
In case of a regular PCB, you just layout the PCB as usual and then do the same LGA footprint eliminating the whole wire-bonding step. And wire bonds would have to be covered in epoxy, of course, so one more step compared to a PCB-based design.
If you don't include the design/layout labor costs (which would be the same in both cases), $25k is more than enough to have a few runs using traditional technology. You don't need any special integrators, you just layout the board as usual, you manufacture it as usual, you place components as usual. There are some details, like the substrate for that PCB will not be FR4 anymore. It may even need to be a ceramic of some sort. But generally it is not that different from your normal PCB assembly.
And all of this only applies if the space is at absolute premium and you must do a separate module. If you are just doing a commercial design (as they list in possible application on their site), then you just place those ICs directly on your main board and be done with it.
Also, if the substrate is actually made out of silicon, then how is it economical with this area? You are literally doubling the area of the silicon required for the project. And silicon cost is a significant part of the IC cost.
One of the feedback panel shows their contractor's (TSMC) feedback. How is this relevant to the technology? Ok, the company is nice to the contractors and orders a ton of silicon, good for TSMC, but says nothing about the technology.
And another panel is form DigiKey, who would not care what that is as long as it lets them sell more chips.
They are obviously trying to pad their resume.
This may provide an advantage to companies doing things like stacked die, where an MCU and a memory or a radio chip are placed in the same package. But again, traditional stacked die design is a well tested idea, so the uses for this technology are limited here.