Are you installing it on Windows XP, or a later 32-bit Windows version? It is likely an OS version conflict, and nothing particular about the machine itself – unless the installer complains that it isn't licensed to be used on that machine, in which case you have to contact the instrument manufacturer.
If not, consider setting up a
Windows XP virtual machine on the dedicated computer. That way, you can isolate the Windows used for the instrument from the network (no viruses etc.), but still have the computer (the "host" operating system, "host" Windows) normally connected to the net. You can also snapshot the virtual machine after you've successfully installed the software, so you can revert back to that state later on.
If it is a completely dedicated computer that you won't connect to net at all, just install Windows XP on it.
(Before you ask why people don't use virtual machines more if they are this useful, the answer is

. They are easy to use, and only impact intensive graphics and disk access slightly – not enough to notice on a normal desktop, except if trying to play 3D games or video or some such.)
I don't use Windows myself, but this is what I'd do if I were you.