If you want to make things easy.
Stick with a single sided load.
Put THT on the same side as the SMT (makes for easier wave soldering).
Rectangular PCB, with space down each side for the conveyor in the printer/placer and possibly wave solder.
Put fiducials (1-2mm round pads, make sure they are blanked out on the stencil, and leave at least 0.5mm gap off resist - makes for better visioning) in the opposite corners, and at the corners of any fine-pitch parts.
Make sure your ident doesn't go over the pads...
Provide proper RS274-X Gerbers, check them with something like GC Prevue.
Let them panelise the PCB..
Check your BOM includes X/Y/Rotation coordinates, adjust so bottom-left of PCB is 0.00, 0.00
Get a list of their preferred common stock items.
Talk to them!