Be awared, the uV virus is a nasty one. I builded several references and have several commercial ones. Stability is the main issue.
While builiding:
-Keep everything clean. No fingerprints on the pcb and reference
-Avoid mechanical stress, for instance mounting it dead bug of cutting a U form out the pcb
-Take in account the seebeck effect, so compensate points with extra solder joints if needed
-Download the keithley book
-More references parallel reduce noise
-Avoid 10 turn trimpots, and i f you use them, make sure theire "span" is very small. For instance one whole turn is a uV. They behave " digital" and are mechanical unstabe. I made one that adjust over 1mV, if I tapped on the cabinet, or lifted it and put it on the table if jumped like 40 to 100 uV. -Replaced the trimpot by low tempco resistors and the trimpot over a 10 ohm resistor.
-Wait with fine adjustment after the burning in. Let it on 24/7 for a few months to stabilize and then do the fine adjudment
-Use low tempco components and low leakage, zero drift/offset opamps like the lt1052 chopper or very good opamp. Metalfilm resistors. Look at the tempco, not accuracy. You want hem stable over time and temp. Not spot on at 25 degrees with a 1000 ppm/C tempco. ( but often low tempco once have good accuracy)
-ovenize it if possible.
http://www.pa4tim.nl/?p=2531 some of my experiments.
But most important part, you will never know how good it is unless you have it calibrated. I have one 5,5, two 6,5 and two 7,5 digit meters. The two 6,5 are calibrated one year ago, one 7,5 is too. They differ 2 to 3 uV ( after about 6 hours warming up) they also have a tempco so measuring at 20 degrees will give other results as at 30 degrees. i'm lucky to have a Guildline standardcel cabinet with known history. The Prema was during he last calibration 0ppm in the 3V range so I measured the cells. Did the same with the two calibrated 6,5 digits. The difference was less as 2 uV and comprnsated for temperature it was sub uV. So the next decade or so I will be close enough to the " golden" Volt for amateur use.