Using a complete ac/dc power supply is a good idea, since this is the most difficult part to get right. A 48V output would be the best, since you probably will only step it down, not up. High power step down is just a half bridge, inductor and some capacitors. High power step up generally involves a transformer (not that hard to do, but more complex than step down).
What I would do:
-find some good PWM source, preferably fast conventional uC (like STM32H7 value line) or something with HRPWM capability (STM32Gx, STM32F343, Infineon XMC1xxx, XMC4xxx). TI TMS320 family also have that but they are a complete pain in the ass to develop for and I would not advise them for someone without lots of previous microcontroller development experience.
-make a gate drive circuit: either an integrated bootstrap driver or a gate drive transformer + dual low side driver
-make a mosfet half-bridge using something rated at ~200V. In general you could go lower with VDS, but this involves more trial and error and fine tuning the circuit.
-calculate capacitors and inductors for worst case conditions. Formulas are available in most datasheets of integrated synchronous buck converters. Formulas scale to very high power levels. The inductor will most likely have to be custom-wound, but this is not difficult at all. Sendust or similar material toroidal cores ara available without any problem, and most manufacturers make available step-by-step instructions on inductor design for most general topologies. Also TI hjas an excellent PDF series "Magnetics design" (google for that term)
-make some sort of feedback loop. In general the theory says you need to calculate transfer function, use Z-transform and loads of other stuff. In reality for majority or use cases a P or PI regulator works fine and you can tune it by trial and error or using one of popular autotune algorithms (eg. Ziegler-Nichols method).
I have built several 1000W+ single-phase step-downs that way. You can also make it multi-phase, which is just 2 or more smaller converter connected in parallel and driven out of phase with each other (180* for 2ph, 120* for 3ph, 90* for 4ph etc).
Unless you need to fit in specified volume or enclosure and therefore require high frequency to miniaturize components, something like 80...120kHz fsw should be a good starting point.
It does sound scary, but it is not. It gets more complicated when you have more constraints like volume, emissions, cost, DFM and so on, but something that is good for a one-off lab power supply is quite easy to build. Also, stupid shit starts to happen when you get into stuff like 5V@300A, but that is a different story altogether.
Some time ago we have managed to fit 3x synchronous step down, 2.2kW each in about 100x170x100 volume (including heatsink, excluding ac/dc), powered from 48V, running at 200kHz, with silicon semiconductors only (GaN is yet very expensive and problematic in implementation and SiC makes sense above ~800V). Unfortunately I'm not at liberty to post photos of that.
By the way... high power is a relative term. I work for a specialistic T&M equipment company and we have some jokes going around about how Insulation Tester guys consider 1Meg resistor "almost a short" and from microohm meter people you could hear phrases like "...u know... some large resistance... like 4 miliohm". Same as motherboard and microwave guys sosider everythin under 1GHz "almost DC". Ask EV charger company about something "low power" and they you'll get something like "uhmmm... under 15kw, right"?