The safe way is to assume nothing aside from not being continuous overload conditions on the input.
High impedance input (not every 10MHz reference drives 50 ohm well and this is standard)
Add a DC blocking cap where you need to in your design, probably better not to assume it
Diode clamping protection is nice, but not always present in gear I've seen and adds some capacitance
Put in a narrow bandpass filter around 10MHz (20, if that's what you're looking as an input, but 10MHz is the standard) and you'll always be getting something close to the right frequency and will always be getting a reasonable sine wave
BNC female (like the front of a scope) is standard
That all said, you can sort of get away with less. This is the 10MHz reference input SMA connector (the cable goes to a BNC input on the back panel) inside a LeCroy WavePro 7200's timing board, and it's got a resistor divider, a DC blocking cap, and some diode clamping, then it's off to what I think is a PIN diode switch to go between the internal and external source.