The switcher could follow the set voltage plus (say) 2 volts, which would mean that the maximum dissipation across the pass element would be 2 * 6 = 12 watts.
Or should I forget using an SMPS and just go linear instead?
That´s a naive calculation for a real lab supply which has to survive any kind of loads.
Let's assume you have a load which switches between 10 Ohms and 0.1 Ohms
at a high switching frequency (above 100 Hz) and a setpoint voltage of 45 V.
During the 10 Ohms phase all is ok. The switcher regulates
its output capacitor to 47V giving a dissipation of 2V*4.5A = 9W.
Then we go to the 0.1 Ohms phase so current limiting to 6A of the linear supply will be done.
The capacitor is still charged to 47V. Output voltage is 0.6V due to current limiting.
Resulting power over the pass element is around 46V * 6A = 276W at least in the first moment.
So you have at least to calculate with the energy stored in the output capacitor of pre regulator times
the maximum possible switching frequency of your load as power dissipation of the pass element.
And: you have to consider the behaviour of the lab supply when switching back from 0.1 Ohms to 10 Ohms
again. In this case depending on strategy of the pre regulator it will take long time until the output reaches 45V again.
With best regards
Andreas