+ Gavin Melville
Attached is another offering, this one straight from the drawing board. It has not been optimized, prototyped or developed.
The circuit uses a conventional voltage regulator circuit (N1), and a current to voltage converter based on a virtual earth shunt feedback amplifier (N2).
The circuit eliminates the requirement for a nano amp ammeter by generating a voltage proportional to IS, the unit supply current. As the voltage is at a zero Ohm impedance, neither does the voltmeter need to have a particularly high input impedance: 10k Ohms upwards will be suitable.
There is little current drain from the 5V reference line.
Under low IS conditions the voltage regulator output is low, so the low-leakage diode D1 is slightly reverse biased. This means that the voltage regulator has no effect.
Under these conditions IS is sourced from the summing node at N2's inverting input, which is supplied with current by the feedback resistor R3. Thus the summing node acts as a 5V regulator, maintaining a 5V supply for the unit.
At an IS of 7uA the summing amplifier out put will be up against the 12V supply line (saturated) and will be unable to supply any more IS. At this point the summing node voltage will drop. When it drops by a milivolt (V DELTA) the voltage regulator, N2, takes over and maintains the voltage across the unit at 5V- 1mV (a VDELTA of 1mV might be a bit tight: 20mV is probably more realistic).
The voltage regulator has the potential of supplying in excess of 200ma, except that a BC337 is limited to around 143 mA, due to heat dissipation, so this needs to be sorted but it is not a major issue.
And that is how it works- I hope
When I started the design you only had a couple of replies, but by the time this design was ready for posting I was surprised to see so many replies: should make some interesting reading.

PS: the OPA192 is pretty good, but there are possibly better opamps for this application. I have initially kept clear of switching opamps on the grounds of low noise, but they may offer some advantages.
The non electrolytic capacitors are polypropylene dielectric. All capacitors are for decoupling.