MLCCs larger than 1206 (3216 metric) can survive okay if they feature "soft terminations," and/or are specified for automotive use, though if you have to use lead-free solder then all bets are off.
Another thing to watch out for with SMT capacitors in this application is violating minimum creepage distance. Sure, the part is *functionally* capable of withstanding 400 or 450VDC, but that doesn't mean a safety ratings agency will accept it, and once you have to start resorting to putting capacitors in series you might as well go with a through-hole part, especially since a metallized film type is the best for this application.
That said, there are some other issues with your circuit as drawn (as well as the way it is drawn - like those funky angles) but as implied by Tim's offer, we aren't here to do your job for you (not for free, anyway).