I made a PCB that has a temp/humidity (ENS210) and VOC sensor (ENS160) and used an ESP32-C3 MCU (Xiao). I found it runs surprisingly hot, so the temperature is not accurate.
Now I've redesigned using an STM32F411CEU6. I put the two LDOs at the bottom and the sensors at the top, ~54mm away. I cut a bunch of 1mm slots and made the traces going to the sensors very long: SDA, SCL, GND, 3.3V, and 1.8V traces are 0.16mm (~6mil) and about 160mm in length. It's a 4 layer board and I kept the long traces on the outer layers, to better shed heat. I held back the copper pour from the long traces but kept signals opposite GND or 3.3V. Hopefully it's a poor antenna.
It looks like this (may have gone nuts with slots, but it's the purpose of the board):

This sensor will be used in a bathroom that has a shower, hidden in or near the exhaust fan or in the duct. It will turn on the exhaust fan based on temp, humidity and VOCs.
Finally my main question:
Given the humid air, how should I treat the board?I will use epoxy filled vias.
I have a conformal coating spray (MG Chemicals 422B, silicon modified acrylic). I can use that (after masking the sensors) but as I understand, it isn't intended to be waterproof. Is it good enough for bathroom humidity? Is there something better?
I could pot the board in epoxy resin, leaving the slotted area exposed (with the conformal coating). There is a
4 wire terminal block that also needs to be exposed. I'm not worried about repair/rework, if the board dies I can just make a new one. However, would the epoxy cause the two NCP114 LDOs and STM32 to run hot, potentially ruining the sensor readings?
I plan to run the STM32F411CEU6 (a 100MHz MCU) at 25MHz. Can I expect that to run cool? Is there a better STM32 pick that is pin compatible with running cool in mind?