Why do you think that?
Because you said move R1 to between Q1's base and 0V. You didn't say anything about Q1's emitter.
You're correct. I apologise. I meant to say between the emitter and base.
The circuit will work the way you show it. However, I don't like the idea of connecting the PIC pin to Q1's base directly with no current limiting. Since the DMP3099L-7 doesn't have a zener in it, I will leave R1 where it is.
Your concern is unfounded. The emitter resistor will limit the base current to a much lower level, than it would be if the resistor was in series with the base. The base current will be equal to the current through R2, divided by Q1's Hfe, which will be around 4.6µA, assuming an Hfe of 100. It will also speed up the turn-off time, as Q1 will never go into saturation, although I appreciate speed isn't a concern here and it will never be fast with such high resistor values.
After reading floobydust's post, I have decided to add a 15 volt crowbar circuit right where the 12 volt supply comes into the box. The power supply "should" never go above about 12.5 volts. But you never know for sure. I would rather take out a fuse rather than damage other circuitry. Hopefully the fast blow fuse would go before anything else did.
I think that's a good idea.If you experience nuisance tripping, you ca add a slow down capacitor to the crowbar and another, slightly higher voltage zener to catch short, high voltage spikes.