I used to make my own boards at home, years ago.. but in my opinion it's just not cost effective anymore. The blanks are expensive in small quantities, so you have to buy large sheets and cut it yourself. Then you have to sensitize it with a photo-resist, and you might not get that coating even, it takes a long time to get expert at it. I always did darkroom boards, never iron-on anything.
Then it's nearly impossible to make anything more than a 4 layer board, and you don't get plated through holes, unless you buy another chemical... and oh, the chemicals. They
have become unreasonably expensive these days for home use quantities. Plus, there's the issue of disposal. I can go on and on....
With the numerous PCB houses online these days, and fast turnaround for small runs, you get a better board with solder mask, silkscreen, PTH, it's often fully tested, and routing, you can even get gold plating.. it's just too cheap to make it at home anymore.
The only reason to do it, as was already said here, is for the fun and experience.