You can also double up on pins, when it's convenient. For example, routing USB through pins 1-6 and 3-4 to improve clamping just a little bit. (The USBLC6 is basically made this way by design, but there are 4-independent-channel types out there too.) Downside is it increases capacitance, so don't do it anywhere you need maximum bandwidth, or where you'd rather have symmetry (one pin per signal).
Tim