Quite some difference between lab equipment SMPSU and a stage guitar amplifier.
Yes of course smpsu designs use a non grounded heat sink at potential. Thats because its safe to do so in an earthed case, and normally used in a dry, dust free environment. But a guitar amplifier has a good chance of user abuse, damp conditions, dust and beer spillage! Along with physically dropping the unit with a good chance of breaking the plastic insulators. Heat sinks are heavier than just a chip. Plus the case is not shielded. Its wood although the voltages go up to 80v, not hundreds. Large heat sinks at AC (anything up to 20Khz in this case) will radiate EM fields. More chance of interfering with other circuitry within the amp, for example causing positive feedback causing HF oscillations. Those then have to be taken into account. If not, the whole amp could become unstable. I could go on...
Marshall do have far better designs certainly not using live heat sinks in their higher range of products. The heat sink is normally placed at the back externally or internally fan assisted. In nearly all cases that i've seen over the years, the heat sink is at ground. Even with designs using this same chip but insulted at the chip - not the heat sink. But in OP's case its not. This is purely a cost cutting exercise and i bet even the Marshall techs had to bite their lips with this one. I would have said something to management if it was me designing it - knowing full well they would have replied 'sorry, we have to'.. Maybe someone reading from Marshall UK could comment for a definitive answer.. But thats how i see it.