The Optocoupler seems to be a peak limiter, and will only operate when the output is near +/- 50v.
At all other times it is switched off, so the resistor you should substitute is its off state resistance, maybe for all intents and purposes open circuit.
The scope photos do seem to show some DC offset, but presumably this is without a load, so may be misleading.
Run the tests again with some sort of dummy load, (Don't need full power, just check the dc offset).
it may just be that the only problem is the Fets.
I would first make sure, using a meter on ohms mode with the amp off, that the 16v power supply ground, the 50v power supply ground, the ground on the op-amp, and the ground on the speaker output are all connected together by zero ohms.
Also, the speaker ground return runs through the headphone jack, which is a switched type, so that inserting a jack plug cuts off the speaker.
This switched jack is notoriously bad at failing, so don't put your dummy load on the speaker cable, put it directly on the power amp, and replace the headphone jack later.