Hi, I think i have a faulty one of those in my 8505A. Did you find a datasheet or suitable replacement for yours? I have a dozen or so 2n4391 I hope I can use.
In the 8505A, these transistors do get hit with -30V to turn them off. The -30V is enough to turn any of the 2n4391-2-3 JFETs off completely, as far as I understand.
My main concern with the 2n4391-2-3 is the V(br)gss (the gate-source breakdown voltage) which is rated at -30V in the Fairchild datasheet; is that perhaps shaving things a little too close?
I tested the V(br)gss on some samples with the Fairchild logo that I have here, and found that they did not actually break down until more than -100V, so perhaps there is no need to worry too much!
Central Semiconductor also makes the same 2n4391-2-3 transistors, and their datasheet gives a V(br)gss of -40V...
Another difference is the Rds(on) difference between 2n4391-2-3. Depending on which circuit you are repairing, this may make a difference - it could even be an improvement in some cases - but it may cause problems e.g. on the A/D board or in other super sensitive areas.
As it happens, I ended up swapping the entire board with one from a spare unit and haven't gotten around to trying this in an actual unit. But now that you've reminded me, I might have a go in the next few days...