Vintage HP test gear uses three different sizes of imperial grub screws;
#4-40, uses .050" Allen key
#6-32, uses 1/16" Allen key
#8-32, uses 5/64" Allen key
As the centres of HP knobs are usually brass & the screws use a coarse thread I've never had a problem removing them. However Tek knobs with steel centres are a PITA if rusted, but usually come out eventually.
If you have a lot of vintage test gear invest in decent Allen keys, cheap ones bend or snap far too easily.

Be careful using force on those small Allens - it is only too easy to come a gutser with those, as Dave might say.
Applying a drop or two of "Weasel P*ss" (50/50 mix of ATF and Acetone) in advance of the procedure can work wonders.
Never needed to use anything like that on HP test gear, if the grub screws are too rusted to come out using just the Allen keys then the rest of the unit is probably knackered too.

David