BF121 is a late 60ies silicon RF-Transistor, typically used in IF amplifiers. And: Yes, the device shown in the photo is a BF121.
S = "Schirm" = Screen.
This was taken over from the germanium RF transistors, e.g. AF124, in the metallic TO-72 case, where "s" is simply connected to the case.
"S" is typically connected to ground.