Uhh, sure I guess?
Network as in what, some arrangement of transistors that works at DC? Or something at RF?
In either case, it's entirely possible the bias wasn't designed to be stable beyond some range of gain or other characteristics, or the capacitance is wrong, detuning the network.
"Transistor networks" in general are Turing-complete, so, you don't have to do much different to have some potentially very different results from device parameters.
Tim