The above mentioned case was the same, kind of random...
If you can find a service manual, otherwise 2221 or 2230 should be close.
Try checking loose jumpers, interconnect and socketed I.C. seating.
Also check PSU voltages/ripple, including locally on the digital board. (Maybe near the more power hungry components, usually the hottest.)
Other things I would look into are squashed logic levels on buses, flaky EPROMS (rewrite a pair on new IC's), finding some something to disconnect that will give you the X every time could also give some clues...
I have a 2230 that I bought cheap and hardly ever use, bought cheap because it had a "display issue" since I have it it has always worked but I can't help think that maybe the 2230 is capable of displaying the X too.