Have you tried running the self-tests
http://www.tek.com/support/faqs/how-do-you-run-self-tests-2465, and do they run to completion without failure?
Does the scope look to be reasonably in cal? Note that the frequency of the compensation output on the 2465B changes with the time base, so you can do a quick check of the timebase calibration by hooking a 10X probe to the calibrator, then running up and down the timebase settings. You should have the same number of cycles on screen from way low until the calibrator is at 5MHz or so.
A common problem with these scopes is leaking SMD capacitors on the A5 control board. If the scope is new to you, and you don't know whether these have been changed, that'd be my first port of call. It's quick work to change them and should IMHO be done preventatively as this is a very common problem. The A5 board is quite easy to get to - pop the case and it'll staring at you from the right-hand side of the scope. A couple of connectors and a couple of screws, and it's out.
The gunk from the caps tends to mess with components that derive the reference current for the DAC on the A5 board. Since the 2465B is pretty much all drive-by-wire, this will cause all kinds of fallout, including trouble in reading back from the thermistors in the attenuators.
Incidentally, the quickest and easiest way to diagnose DAC reference trouble is to measure the 1.36V and the -1.24V reference voltages on the A5 board. Some versions of the board break them out to test points, but on other (later?) versions you have to hunt them down to component legs or the like.
If those voltages are grossly off (say more than 5% or so), you have a smoking gun.