Thank you for the reply. That's basically what I'm wondering about, will there be arcing across the traces or components in the microcurrent if it's used at high voltages.
Oops, missed the reply ... better late than never though :
You misunderstood what I was trying to say ... you seem to believe that the high voltage makes a difference to the uCurrent in normal operation, it doesn't because your DUT takes the voltage. The problems only occur if your DUT goes low impedance, like for instance an Ion Chamber arcing or if your power supply ramps too quickly ... if it arcs the uCurrent could destruct instantaneously regardless of how much current your power supply can deliver, simply from energy stored in (stray) capacitance. Simply depends on how much energy there is, the input resistors and the protection diodes inside the opamps provide some protection.
So in summation, you don't need input protection simply because you use high voltages ... you need input protection if your DUT has the potential of going low impedance. What kind of input protection depends on how much energy you can expect to dump across it.