Chuki, you're opening a can of worms with all your questions

To explain it all thoroughly, it would certainly take much more than just a short posting.
First, trust me that one division on your scope is equivalent to 25LSB. The total screen height is 200LSB and there are 27LSB headroom above and below.
There is no significant difference between channels regarding noise, but the calibration has only finite resolution and cannot cancel out very small offset errors. This is why offset calibration can never be perfect for the very high sensitivities like 500µV/div and this is also why there will always be a slight offset difference between channels.
Yes even the noise can appear different with certain channel gains, just because it depends on the precise vertical position (= internal offset) setting how often the LSB of the ADC (analog to digital converter) is toggled. As I said before, one LSB of noise is always to be expected, and if it's less than that, it's just a special situation that can easily change anytime or needs not be the same on some other channel.
GND coupling is a very special case and it does not really shorten the scope input like it did on old analog scopes. It just shuts off the output of the VGA (variable gain amplifier) of that channel, so some tiny offset error of the ADC as well as some numerical offset manipulation in the signal processing path might still cause a small visible offset.
If you are really interested in a more thorough explanation how these things work, feel free to read my posts in this discussion (starting at reply #129):
https://www.eevblog.com/forum/testgear/siglent_s-new-product-sds2000x-series/msg1889885/#msg1889885Yes, it is a different DSO (SDS2000X), but the principles are exactly the same.
As to Quick Cal, this is just fast calibration "on the fly" whenever the DSO detects a major temperature difference and/or a change in the channel gain setting. It will cause a a short "hickup" of your measurement and then results are more accurate again. This should not happen anymore once the scope is properly warmed up and ambient temperature remains fairly constant.
Some people don't like this feature, so it can be turned off or on, just as desired.