A friend of mine has a TDS210 and is thinking about connecting it using good quality 1000x probes to a 600 V thermionic valve circuit. How safe would that be? Also if I'm hijacking the thread too much, please tell me.
As long as the valve circuit is floating or grounded, this should be fine. The ground clip of a 1000x probe is still directly connected to ground. Even a good 100x probe should be sufficient, assuming it's 600 VDC or low frequency AC. 600 V RF is a totally different ball game. Note that the bandwidth of the HV probes designed to multimeters is quite limited (maybe a kHz or so). If it's a real scope HV probe (eg. Tek P6013/6015/6015a), then it will have decent bandwidth.
Be careful with AC coupling, though. The maximum voltage in AC coupling mode is determined by the scope, and this is likely less than 600 V (check the manual).