I'd think twice before using this kind of circuit (but that said, I have done it myself in the past, although amplifier was just ordinary opamp connected as difference amplifier), but since you are going to do it anyway, put at least several, say, 5, 1M resistors in series, normal resistors can only take 250 volts or so. That also ensures that no single resistor failure will cause a direct hazard. That would not probably meet IEC61010 requirements but it is a start.
For functional protection, you can put those 1N4148 clamping diodes to supply rails directly at amplifier input (where voltage is low), that should work ok.
Regards,
Janne