As above it depends and I can't really give an opinion of your situation without knowing more of what you're trying to accomplish. Given that 12V and 24V are often used in my industry I'll share some perspective and experience of my own that may or may not be in any way relevant to what you're doing.
I work with PLC's to monitor/control equipment and 24VDC is a frequently used voltage in this industry both for signaling (DI/DO) and as a power source. The primary voltage that I use in the systems I put together is a nominal 12VDC (from batteries, fed from a mains or solar charger or both if redundancy is required) which I then step up to 24VDC using DCDC converters for things that need it.
The way I see it is that your DCDC is another point of failure, so don't rely upon it, and if you need to duplicate it.
So, my core equipment such as PLC's and Radios and whatnot are all fed from the 12V, whilst loop current sensors that need 24V are fed from DCDC converters stepping it up to 24VDC
Rather than have one converter take out all of my loop current sensors each sensor gets its own DCDC converter.
If I'm for example monitoring motors then each motor will get its own 24V converter to monitor the status of things such as overloads, contactors, phase fails, etc. This way if a DCDC dies I'm only loosing the monitoring of one motor, the other motor (there's always redundancy!) is still monitored.
Likewise if a wiring fault shorts my 24V's out then the DCDC will sit there with it's overload light on and the monitoring of the other motors is just fine, with no potential to knock out power to the PLC.