If the point the pressure is measured is downstream of the throttle, then yes, there will be both positive and negative (relative to atmospheric) pressure.
Typically, on a trailing throttle at high rpm, minimum pressure will be around 20kPa(abs) and maximum pressure depends on how hard your turbo boosts, but most road cars will be running around 1bar boost (200kPa(abs)). High performance or diesel engines can run up to (and sometimes over!) 2bar boost (300kPa(abs)).
I would suggest that you need as minimum a 2bar range sensor (either 0 to 2bar(abs), or -1 to 1 bar(g))
Depending on the display you are going to use, there are plenty of pcb mounted pressure sensors that output a 0-5v signal that make interfacing to a microcontrollers ADC very easy indeed:

0-5v means you only need a tiny amount of analogue input filtering to read the value, rather than messing around with op-amps etc. (for high accuracy, you could calibrate the device in software)
If you mount all the electronics in the gauge itself, then you have to run a pressure taping pipe through the bulkhead to the engine, or you use a remote sensor and run the wires through. However, you'll find that suitable rated (environmental protected, vibration and temperature proof etc) remote sensors are a LOT more expensive.