Speaking of physical harm, I should mention that a woman fell asleep while driving and her car went into the opposing lane and was hit by a truck. She was crippled.
I fell asleep while driving one night. My truck went off the road, over the side, flipped over a couple of times and fell down the hill. When I woke up, I was very confused because I could not see the road in front of me. It just wasn't there. I thought for a minute that I was dreaming. I was lucky. I survived without injury. If I had been driving a small, lightweight car, I too would probably have been maimed or killed. But I was driving a large, heavy, sport-utility vehicle and was strapped in.
I generally need six hours of sleep per night. But when I'm physically exhausted, I need more sleep. When I fell asleep at the wheel, I was physically exhausted.
So a sleep disorder can kill. Or worse, maim.