Don't be afraid of advanced multilayer boards. In volume even advanced PCBs's price is usually insignificant compared to parts cost. They are only expensive for the first time due to large tooling cost, but this payment is paid only once for the specific set of Gerbers (and this usually happens when you build last pre-production batch), after that you only pay for actual boards and finish. To give you an idea, my last order for 10 impedance controlled 6 layer PCBs (10x10 cm each) was $148.95, and of those $86.51 was tooling cost (58% of the price!), and $30 for ENIG 2um finish (flat rate), so actual PCBs were only $32.44 for 10, or $3.24 each. And this is for only 10 boards, if you order more boards - the price per board will go down significantly.