It would be nice if you can use it as-is as PC hosted 6809 development system, but then you have the aggro of figuring out its ISA bus interface, + finding and maintaining a PC with a slow enough ISA slot, but still with a recent enough processor to run a reasonably current OS to support available FOSS cross development toolchains.
Realistically, it makes more sense to gut it for the chipset and build your own board, possibly with a Pi Pico 2 (for the RP2350's 5V tolerant GPIOs and PIO engine) providing EPROM emulation and debug access via USB.