I know you can set/burn fuses, and with external circuits wired up, you might overheat stuff, or apply the wrong voltage to a pin....
But with just power and GND, on modern MCU's, can you ever set something that internally conflicts, and can do bad, unpredictable things or even damage the MCU ??
And for port protections, how many MCU's pins would have O/V voltage, or OVcurrent, or over temperature sensing ?
I'm sure some MCU's have that on certain pins, but how common is it ??