Mostly agree with ve7xen here, even though that's not a popular opinion. But that's just how reality has unfolded, and no, even though systemd is not all great, it's not just because of some nasty conspiracy against Linux. It's just that it's reasonably homogeneous and just works for a majority of users.
I can understand people willing to stay away from it and/or thinking it's not in the spirit of Linux, and there is some valid points to that, but fortunately, there ARE distributions that do not use systemd out there, and quite a few that do but can be set up to use something else instead.
And yes, I don't get what the topic has anything to do with systemd either.
Especially if the OP wants direct access to the sound card with "bit-exact" samples, I would suggest as I (and others) have mentioned, using ALSA. (JACK is another option, but it's unnecessarily "complex" for what the OP wants to do IMHO.) Unless you have a very specific need, you can directly use the utilities from alsa-tools and call it a day. It works fine with any "sound card" I've ever tested on a variety of distributions - ALSA will always be there as it's an integral part of the Kernel now AFAIK. You may just need to install alsa-tools if the package is not already installed.
As to using ALSA directly when PulseAudio is active, it's certainly possible. You don't need to kill Pulseaudio, at least if you use an additional sound card. Right now I have a Linux box running Gnome with PulseAudio running as well, and a Presonus USB sound card. It can be accessed using alsa-tools while PulseAudio is running, you don't need to kill it. (It might be necessary if you only have ONE sound card in your system, but if you're sampling audio with some requirements about quality, I would suggest using an external card anyway.)