If the cap values are going down (or up- very common) or the dissipation factor is high (I refuse to deal in ESR, that's for switching supply folks), get 'em out of there. If the value and loss are OK, don't expect any improvement. Also, if the value and loss are OK, and you don't see any physical problems, the chances of that cap failing any time soon are minimal. Here's a hint. If you want low dissipation factor, and the part will fit, go up a voltage level. If you look at the manufacturers data, dissipation factor decreases as voltage ratings go up, at least to 63 or 100 VDC. I'm not suggesting putting very high voltage caps in low voltage circuitry, but I will always avoid the poorer performing 6-16 volt parts and use 25 or greater. Very low voltage caps also seem to fail sooner. There are also some linearity benefits and no significant downside to staying away from the lower voltages.