Variable input resistance of the MUTE/DIM module shouldn't be a problem, as it seems to be driven by some line receiver chip through nothing more than a bunch of relays, unless I missed something.
I missed the mono mixdown mode involving R54 and R55.
This circuit has 11kΩ output impedance and is loaded by MUTE/DIM. In passthrough mode, MUTE/DIM input impedance is 5kΩ (simply the two volume pots) resulting in 10dB extra (maybe unexpected/unwanted?) attenuation. In 20dB mode, the loading is 38kΩ and attenuation is much lower (of course the 20dB attenuator still provides its own 20dB on top of that).
If this is a problem, maybe R54 and R55 could be reduced (also better for noise), or the output of the mono circuit buffered. You can also modify the attenuator to have constant 10kΩ input impedance (my initial suggestion) so that enabling mono mixdown introduces constant 10dB loss, regardless of 20dB attenuation or not.
I don't know whether this is your intent or not, but enabling multiple bus selection relays shorts the input buses together.