Depends on the extent of damage. I've never seen data on how fast the damage accumulates (presumably, it's a dosage measured linearly by charge), and to what currents it causes problems at (presumably, higher doses cause a higher current threshold effect?); you'd have to run trials yourself to see.
Also interesting to see, would be the effect on low frequency noise (0.1-1000Hz?).
Supposedly, it can also be partially annealed at soldering temperatures.
Maximum safe level? Vebo is measured at 10uA, but beyond that, Idunno. To what end? If you want a good zener, get a real one; much less noise, and guaranteed voltage level. If for repetitive conditions in an amplifier or switching circuit, use an antiparallel (E-B) protection diode (or a lower voltage bidirectional TVS, or a series prevention diode).
Tim