you do have ps2 male to usb female but the hardware put on them need to be compatible
and maybe on vogon web site, there is some card interface or maybe some github projects who could do the job ...
you're dealing with 2 different technologies and switch between them as you know can be done to some extent, you have some pci card who can add usb 2.0 interfaces, even some oldies ISA card slots who can add usb 1.0 support ...
and keeping an legacy system and doing dev on it is not good, unless you use some legacy who as a very long term support ?
why don't you use virtual desktop / machines inside windows 10 or 11 ?
what's this legacy can do vs a more recent era machine can't ?
isa to usb
https://www.ebay.com/shop/isa-card-usb?_nkw=isa+card+usb but have only one port, not sure if you can add a hub on them
plenty of pci 32 bits to usb 4 and 5 ports on ebay or elsewhere ?
unless i absolutely dont catch your needs ?