Found out this : the Rev E had many problems
https://coolate.com/blog/blog/2015/02/23/its-alive-makerbot-replicator-repaired/
http://www.akeric.com/blog/?p=2836
Actually the biggest fault on the RevE was just the power regulation. Besides that they are fine. The later clones of these boards made by FlashForge, Geeetech, Wanhao, CTC, they all went to a switching regulator for the 5v rail, that solved 99% of the issues.
On an original Rep1 RevE board you really only need to replace the 5v linear regulator with a switching regulator, i like to use a Murata Power part, OKI-78SR-5/1.5-W36-C on a small circuit board i designed and built a case for. The board includes poly fuses just in case if SHTF, but for the most part they have really good OCP and OVP, and just shut down if anything goes wrong.
The other problem on the RevE board was that they powered the 3.3v regulator from the 24v supply and it was just too much input voltage for them, so they modded their boards shortly after and cut a trace and jumpered the 5v output to the 3.3v input, which made that regulator behave, but put even more load on the 5v regulator, and it killed a lot of boards. The worst part is the regulator would fail and short 24v to its output, frying every IC on the board. I have rebuilt a lot of popped boards, its time consuming but cheaper then new boards.
This is not to say that the RevG and RevH boards don't have their faults. Their biggest fault is their tiny 150mA rated FET's for the cooling fans, get a fan that starts to gum up or stop one on accident and it pops the FET, i fixed that by putting on 3A rated FET's for the fans. They do pop a Heater FET now and then, but usually only due to a dead short on the heater, and those FET's are a few minutes job to replace so its not overly terrible.
All in all, i much prefer repairing the RevG and RevH boards, generally its a couple small jobs on them and out the door. When someone brings me a dead RevE board its usually a complete overhaul to get them working again because they had a 5v regulator blow. I have three Rep1 printers, the oldest is over 6k hours on the clock, but i had modded everything on it when i got it, around 150 hours when i bought it used. Its been solid ever since. The other two were rebuilds i bought as dead printers, blown RevE boards, rebuilt them and they have 2-4k on them now as well. My latest printer is a Rep2X that was also a dead printer but in excellent shape other then a blown board. Quick repair on that and cleaning and it was running just fine, i think that one is nearing 1000 hours now.