Only general OKi MFR/Metcal MX soldering experience here, no desoldering.
I've had the MFR-1110 for ~3 years. It has performed flawlessly, no problems whatsoever.
We have Metcal MX-5000 (and a 5200 recently) stations at work, and I haven't noticed any real difference in performance, but I haven't tested it thoroughly either.
The quality feel is a bit less on the MFR.
The handpiece connector seems a bit less rugged, looks like a DIN. It is latched and I think it's OK.
The handpiece itself is all plastic, no aluminium like on MX. But it works well, I can solder all day and it stays cool.
The cable is slightly thicker and less flexible, I think? Not a problem, though.
On the positive side: The power unit is cast aluminium and seems very solid. I like the design, looks like a heatsink
I have never missed temperature adjustment, no need for that.
Overall a huge step up from my Weller WECP-20 from 1992 (which is still going strong, btw).
Great value for money!