1. You don't specify any currents.
2. There is not much point in pouring the chassis ground over the PCB, as that is actually chassis ground, which is only connected to the converter housing and to the 4.7 nF and 22 nF capacitors that work as safety or EMI suppression capacitors (they play the same role as Y capacitors in an AC supply; but note that Y caps are not rated for DC). I would create separate ground planes for V- on primary and secondary (well separated), and keep the chassis ground, not as a plane, but with a separate connector, that should be connected to the metal casing (if this is housed in a metal enclosure).
3. The aforementioned capacitors C4, C5, C10, C11 as per the data sheet should be film capacitors rated for the high voltage, and they should be rated also for DC voltage. For C2, C3, C12, C13 use high voltage ceramics or use film caps in both places.