I went down much of the same path you are going - figuring out microscope basics, and it's been awhile since I used the scope so I might have something wrong here. Without a doubt jfiresto knows more about microscopes than I do, so if I get something wrong and he corrects it, go with what he says.
Having said that, here's what I'd recommend.
Put the Barlow lens on that you think you are going to use over a PCB with some discreet components such as ICs with legs. Set the lighting so you can clearly see a particular IC with legs, maybe with some writing on the top of the component. Notice the direction of the light, shadows, etc.
With both eyes open and looking into the eye pieces move the PCB so the targeted component sits centered in the field of view.
Try to focus as best you can up close, zoomed in with the head focus control, so the writing on the center targeted component is highly sharp. When you get it as sharp as you can with the head focus control, then close one eye and adjust the eye piece for your eye that is open to make it as sharp as possible. Then close the adjusted eye and try to adjust the other eye piece to make it as sharp as possible. Open both eyes and confirm that the view is sharp. If not, redo everything up to this point, and then proceed.
Now zoom out, all the way to fully zoomed out. Ideally the microscope will retain sharpness on the targeted component all the way zoomed out to the widest view. If it isn't sharp, redo everything up to this point, and then proceed.
If you are lucky (and the scope is good) you should be able to see the targeted component sharply in focus and most of the rest of the wider viewing area sharply in focus, however it's likely that the overall viewing area edges will not be quite as sharp as the center component you set as the target. Then when you zoom back in you should go back to your optimum sharpness on the target component.
After doing this procedure a few times you might start to notice that what you thought was well focused on the zoomed in center target could potentially be improved based on where exactly you were focused. At this point you might start to notice how much depth of field the scope reveals. For example, when zoomed in maybe the component label is sharp at the top of the component but by the time you look at the legs of the component where they meet the PCB maybe they will be a little less sharp. Some optics allow more depth than others.
After following this you should have good control over the scope and be able to set it for it's best performance, which should allow it to provide parafocal operation, ie it should retain focus when zoomed from in to out, and then zoomed from out back to in. It's possible that it will not be 100% parafocal, but ideally it will be substantially if not perfectly parafocal.
At this point you are ready to enjoy soldering with a good view.