I heard this great audio presentation by Limor Fried (Ladyada) and Phillip Torrone.
They talk about how they run Adafruit, their open source hardware company, and I highly recommend everyone give it a listen.
It was recorded at on of the HOPE conferences, and I originally heard it HERE, but it now seems to be missing.
So I have found the file and hosted on my server, if anyone minds please let me know.
The original source is HERE.
Podcast: Download
Podcast (podcast2): Download