..The SARS-Covid-2 virus has a genome with about 30,000 base pairs, that means (crudely) it can only code 10,000 amino acid sequences, quite a few of which are overhead. Compare that to a computer virus with 30,000 bytes assembler instructions and 10,000 actual instructions. That little genetic material has to code for the structure of the virus, how it gets into a host cell, how it gets that host cell to manufacture more virions and so on. ..
just see this:Quote...We hypothesize that SARS-CoV-2 does as well.Nice hypothesis. Let me know when you’ll find a peer-reviewed article that starts its conclusion with the phrase “we established” instead of “we hypothesize”.
well if you do not like how science works you can always try cow urine
..The SARS-Covid-2 virus has a genome with about 30,000 base pairs, that means (crudely) it can only code 10,000 amino acid sequences, quite a few of which are overhead. Compare that to a computer virus with 30,000 bytes assembler instructions and 10,000 actual instructions. That little genetic material has to code for the structure of the virus, how it gets into a host cell, how it gets that host cell to manufacture more virions and so on. ..The virus is a chunk of RNA encapsulated into "the debris" of the cell's outer membrane (the cell which burst because of the mass-produced RNA). Thus the "how to get into the cell" is not coded in the RNA itself, but specified rather by its encapsulation - and while it is made of the cell's outer membrane the barrier to enter into an another identical or "similar" cell is almost nil, imho.
Structural biology
Each SARS-CoV-2 virion is approximately 50–200 nanometres in diameter.[50] Like other coronaviruses, SARS-CoV-2 has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins; the N protein holds the RNA genome, and the S, E, and M proteins together create the viral envelope.[51] The spike protein is responsible for allowing the virus to attach to the membrane of a host cell.[51]
For the first time since 1973 our PM addressed the country.
The strategy is to isolate as much as possible the elderlyand vulnerable till its over. The rest of the population should over time get the virus in a natural way, so they get immune after they recovered so they don't pose a thread anymore after a certain period of time.
Does anyone know if the PCR tests being commonly done by public health services are quantitative? How about the antibody tests? I've read articles that mentioned both viral load and detected/not detected results.
At least in the USA, the PCR tests are pass/fail tests. The test basically slices and dices the sample RNA, making copies each time, matching on 3 different sample patterns found in the virus. Each one is tagged with a dye which is then measured (after each copy iteration). This will generate a curve of the fluorescence at a specific wavelength. They plot this on a graph and if all 3 different dye tags cross a specific threshold within a specific # of replications, its a positive test.
Does anyone know if the PCR tests being commonly done by public health services are quantitative? How about the antibody tests? I've read articles that mentioned both viral load and detected/not detected results.
At least in the USA, the PCR tests are pass/fail tests. The test basically slices and dices the sample RNA, making copies each time, matching on 3 different sample patterns found in the virus. Each one is tagged with a dye which is then measured (after each copy iteration). This will generate a curve of the fluorescence at a specific wavelength. They plot this on a graph and if all 3 different dye tags cross a specific threshold within a specific # of replications, its a positive test.
So how do they do an "N-gene-specific quantitative RT-PCR assay", as described in this article:
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30113-4/fulltext
Is it a lot more difficult than the pass/fail test you describe?
For the first time since 1973 our PM addressed the country.
For the first time since 1973 our PM addressed the country.What happened in 1973?
For the first time since 1973 our PM addressed the country.What happened in 1973?
For the first time since 1973 our PM addressed the country.
The strategy is to isolate as much as possible the elderlyand vulnerable till its over. The rest of the population should over time get the virus in a natural way, so they get immune after they recovered so they don't pose a thread anymore after a certain period of time.Just for clarity: it wasn't the same PM as in 1973. Still it is impressive. Never thought I'd see the day but yet here it is.
His main message was that most people will get infected at some point (which is what Merkel; the PM of Germany also stated a couple of weeks ago). The efforts are aimed to control the outbreak so health care can keep up. Makes sense to me because that seems the only way to me to keep both the economy going and reduce loss of life.
Even countries like Canada are showing a 25% increase in the number of cases just in the last 24 hours!
However that's going to go up drastically if we can't limit the rate of increase so that the medical systems can deal with it.
But you've missed an important point: at this point it little matters what happens to the economy. The entire planet is faced with the possibility of MASSIVE numbers of deaths due to overloaded medical systems. Right now, they're making hard decisions about the best way to keep as many people alive as possible. Yes, short of some sort of vaccine being invented EVERYONE is going to get it. And even in the best medical conditions, an average of 3.4% of the infected people are dying. That's 10 million people in the US alone and about 230 million world wide. However that's going to go up drastically if we can't limit the rate of increase so that the medical systems can deal with it. Go look at Italy right now, they CAN'T deal with the current rate of increase, Iran is just as bad, South Korea was but now seems to be getting some control on it. Spain is losing control, so is France and Ger
That's interesting. If an animal is infected, especially a pet (that people are very likely to get close to), how can it not happen?
Even countries like Canada are showing a 25% increase in the number of cases just in the last 24 hours!What did you expect if Canadian idiot health officials were saying ,as the toll was rising in China, if you see a Chinese person come say you support them and shake their hand.
In Italy the infection rate is slowly getting lower and lower although the situation is not the same everywhere (there is even a province with zero cases).
It takes time to see the effect of quarantine. I'm sure anyway that we'll have to wait at least another month before getting where China is now.
In Italy the infection rate is slowly getting lower and lower although the situation is not the same everywhere (there is even a province with zero cases).
It takes time to see the effect of quarantine. I'm sure anyway that we'll have to wait at least another month before getting where China is now.
All in all the only real number you can use as a gauge to say anything meaningfull about the spreading of the Corona virus is the number of deaths.
Coronavirus: German Big Brother cast to be told about pandemic live on TV
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IMHO, this means two things:
- Germany is still at the very beginning of the wave and not many critical cases had the time to come to closure.
- We have a good test coverage...