IMO, what connector would you like to suggest as an alternative, as No matter what you do, there will be Copper - Solder - Some Metal - | - Some Metal - Solder - Copper, So may as well beat the curve and just use solid core copper wire to bridge the gap.
I've bunched the integrator up to make that node much smaller, and added the updated guard trace, I'll also seperatly guard the integrator output with analog ground once I figure out the new placement for the slope amplifier.
For the input mux, you have the GND, Zener and Temp inputs all being low impedance inputs, so if you wanted to do a double buffer Its not a problem, would just mean buffering the 5 other inputs, or putting something else we want on those inputs that is already buffered.
Edit: when I work out what ferrite to go with, I'll nudge it up a little and just connect directly across 4053 pin 1 and 3, leaving the 2-5-12 node to have a similar orientation ferrite positioned across 4-6 but not actually connecting to that ground,
Edit2: for true volt-nuttery I will be removing any silk screening that touches the integrator node or guard trace, just takes some time.